Cambodia’s strong point is definitively not wheelchair friendly accessible places. Streets and sidewalks are often not in good conditions and very few buildings have been conceived with reduced mobility users in mind, with the exception of airports and luxury hotels.
Access to the Angkor temples complex, the country’s main attraction, is also rather complicated. The floors are uneven and there are obstacles all over, and steps.
On the plus side, taxis are very cheap and the locals are very helpful, and hiring a local assistant is also very affordable. Most smaller hotels have rooms on the ground floor, and you can also rely on the services of an accessible tour operator, which can make the holiday smoother or help organise the sightseeing and tours.
There are three international airports in Cambodia: Phnom Penh, Siem Reap et Sihanoukville (mostly internal flights between Phnom Penh and Siem Reap). All the three have special assistance services and accessible toilets. More detailed information is available in their websites.